Berberine - Health or Hype?

Over the past few months, berberine has exploded across social media as the next weight loss miracle pill with some calling it ‘nature’s Ozempic’. While I think these weight loss claims are exaggerated, it is true that berberine has been shown to provide support for a variety of conditions including irritable bowel syndrome, polycystic ovary syndrome, high cholesterol, heart disease, type 2 diabetes and yes, weight management. Today, let’s look at three of these, blood sugar, cholesterol and weight loss.

Berberine has been extensively studied for its ability to lower blood sugar in clinical trials. It appears to work in several different ways including decreasing insulin resistance (effectively making the body’s insulin more effective) and increasing glycolysis, the process of breaking down sugar in cells. According to research, when compared to common medications like metformin, berberine was as effective as drugs, but with no significant side effects.

Berberine has also been shown to help reduce blood lipids (cholesterol and triglycerides). Compared to statins, a class of drugs commonly prescribed for high cholesterol, berberine was found to lower total and LDL cholesterol but unlike the medications, additionally reduced triglycerides while increasing HDL.

When looking at weight loss, the benefit appears to be from activating an enzyme inside cells called AMP-activated protein kinase (AMPK). AMPK plays a key role in regulating metabolism and energy levels and is found in cells throughout the body. While more studies are needed, preliminary studies show promise. One study from 2012 found that after taking berberine for 12-weeks participants lost an average of five pounds, while other studies found reductions in body weight, body mass index, and belly fat.

While I always urge caution when social media claims sound too good to be true, berberine has been shown to provide a wide variety of health benefits without major side effects and therefore, may be worth a try. One note - berberine may interfere with the absorption of some antibiotics. Also, because of its ability to lower blood glucose, it is recommended to closely monitor your blood sugar levels if you are already taking oral hypoglycemic drugs.

If you’re interested in trying berberine, one excellent option is Vital Choice’s Berberine. It provides the studied amount of 500mg of berberine HCl per capsule from sustainably grown barberry. Another great option is Enzymedica’s new Berberine Phytosome offering 9.6-times better bioavailability and Natural Factor's Berberine.

Mike Ventresca is owner of Vital Choice Health Store located at 9243 Sprague Road in North Royalton. The phone number is 440-885-9505. This information is not intended to diagnose, treat, cure or prevent any disease.