How to Tame Your Zombie Cells

April 14, 2023

Strengthen Immunity and Dampen Inflammation

This article originally appeared on TasteForLife.com.


Zombies are the stuff of legend, living dead that, depending on which movie you watch, are coming for everyone. We all have “zombie” cells in our bodies that make their presence known as we age. Zombie cells have become a popular way to describe something called cellular senescence because these cells act much like the zombies of our nightmares.


What are Zombie Cells?

Senescent cells have stopped dividing and are waiting to be removed from our body by the immune system. These cells are useful when we are young. They allow our body to put the brakes on cells that are either not working properly, are potentially cancerous, have finished a specific job (like scar formation as part of the healing process), or have reached the end of their useful life.


Senescent cells get their zombie name tag because they remain in our body in a state of suspended animation, secreting chemical messages that alert our immune system they need to be removed. When we are young, our immune system handles this job like a boss, but it falters as we age, maybe because it’s getting tired or because the increasing numbers of these cells start to overwhelm it.


Effects of Zombie Cells

Inflammation

  • As senescent cells start to build up, the chemical messages they are secreting cause negative effects on the cells around them. The chemical messages trigger inflammation, and these zombie cells may be the reason we see the increasing levels of inflammation that occur with older age.

Disease

  • Ongoing low-grade inflammation triggers processes that can lead to disease. Laboratory studies show even a few senescent cells can accelerate aging, or at least the symptoms of aging, like cancer and other diseases. Even the more aesthetic side effects of aging, including the graying of hair, worsening vision, and skin wrinkles, have been linked to cellular senescence.

Immunity

  • Laboratory research also suggests that a high senescent cell burden is the reason older individuals react so severely to COVID-19, and that treatment with fisetin, a natural senolytic, may improve immune response to COVID. This insight is now the subject of a clinical trial by the Mayo Clinic to see if the improved response can be replicated in humans.

Treatment for Zombie Cells

Once researchers realized having senescent cells in our body is not particularly good for us and that we have increasing levels of them as we age, they started looking for ways to remove them. Luckily for us, it turns out that killing zombie cells may be easier than knocking off those zombies of the horror story kind.


Scientists have found some simple strategies to limit the number of these cells in our body. These strategies include: regular exercise; a regular program of fasting—missing breakfast from time to time is good, missing breakfast and lunch occasionally is even better; maintaining a healthy weight (fat tissue seems to be a magnet for senescent cells); and taking cellular health supplements such as senolytic complex.


These actions can work together to help you keep your inner zombie at bay and may help reduce the risk associated with high levels of senescent cells in your body, especially as you age.


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Selected Sources:

“Fisetin for COVID-19 in skilled nursing facilities: Senolytic trials in the COVID era” by B.P. Verdoorn et al., Journal of the American Geriatrics Society, 8/10/21

“Senescence and cancer: A review of clinical implications of senescence and senotherapies” by L. Wyld et al., Cancers, 7/31/20

“Senescence in health and disease” by S. He and N.E. Sharpless, Cell, 6/1/17

“Senolytics reduce coronavirus-related mortality in old mice” by C.D. Camell et al., Science, 7/16/21


By Michael Ventresca July 7, 2025
Over the years, I’ve tried just about every type of multivitamin out there: tablets, capsules, raw food blends, fermented formulas, you name it. And while many are a clear step above your big-box brands, it’s rare I come across one that actually makes me want to switch. Recently, I started taking the True Grace 50+ Multi , and I’ve been genuinely impressed. First, it checks all the right boxes for me. It’s made with fermented, whole-food-based nutrients that are easier on the stomach and better absorbed. It’s free of synthetic fillers, artificial colors, GMOs, and gluten. What makes this formula stand out is what it offers beyond the basics. This isn’t just another multivitamin with the usual laundry list of nutrients. True Grace 50+ is designed with targeted support for four key areas of healthy aging. You’ll find Lion’s Mane mushroom for brain health, CoQ10 for heart and cellular energy, and MenaQ7 (a patented form of vitamin K2 ) to guide calcium to the bones instead of the arteries. It also includes antioxidants to support long-term vision, which is a growing concern for many of us over 50. What really caught my attention, though, is ergothioneine , a naturally occurring amino acid often referred to as the “longevity vitamin.” It helps protect cells from oxidative stress and supports brain, heart, and skin health. Most multivitamins leave it out entirely or include only a token amount. This formula delivers a full 5 mg per serving, a dose that actually makes a difference. While the 50+ formula is what I personally use, True Grace offers a full line including Men’s and Women’s core multis , 40+ versions , plus a prenatal for moms-to-be. All with the same focus on clean, effective nutrition. Do I still believe in other whole-food-based multis? Absolutely. But this is the first time in a long while I’ve actually made a switch. And I’m glad I did. Mike Ventresca is the owner of Vital Choice Health Store located at 9243 Sprague Road in North Royalton’s Timber Ridge Plaza. The phone number is 440-885-9505 , or visit VChoice.com .
By Michael Ventresca May 9, 2025
Whether it’s separation anxiety, fear of thunderstorms or trips to the vet, watching your furry friend feel overwhelmed is never easy. Just like in humans, chronic stress can take a serious toll on a dog’s emotional and physical well-being. Over time, anxiety can negatively impact digestion, heart health, and behavior, affecting your dog’s overall quality of life. The good news is some of the same natural remedies that help humans manage stress can also be incredibly beneficial for dogs. Of course, the dosages and formulations must be carefully tailored to meet a dog’s unique needs. Today, I would like to discuss a few natural remedies that can help support a calmer, more relaxed dog. Research shows that L-Theanine, an amino acid found in green tea, stimulates alpha wave activity in the brain, promoting a relaxed yet alert state. This helps dogs stay calm without feeling sedated, since sedation can sometimes upset and confuse dogs, making their anxiety worse. GABA (Gamma-Aminobutyric Acid) is another valuable tool. Often called the “feel-good neurotransmitter,” GABA helps calm nervous system activity and promotes a balanced, stable mood. Calm by Vital Planet combines both L-Theanine and GABA with additional soothing herbs, such as chamomile, lemon balm and valerian, along with a unique blend of flower essences, to help anxious dogs feel more secure and relaxed. It is available in both chewable tablets and soft chews. Finally, Calm, along with all Vital Planet’s pet products, is certified by the National Animal Supplement Council, ensuring exceptional quality and safety. Mike Ventresca is the owner of Vital Choice Health Store located at 9243 Sprague Road in North Royalton’s Timber Ridge Plaza. The phone number is 440-885-9505 , or visit VChoice.com .
By Michael Ventresca January 14, 2025
When it comes to supplements for weight loss, I often tread carefully. The market is flooded with unrealistic claims promising effortless transformations—and let’s be honest, those simply don’t exist. That said, natural products can enhance your weight loss efforts, but they’re tools in the toolbox—not magic solutions. Today, I’d like to share a few of my favorite places to start. First, it’s important to understand that there’s no one-size-fits-all solution. The best way to find the right option is to identify your greatest obstacle: appetite control, fat burning, or metabolism. While we can’t cover all the options in one column, the key takeaway is that there are options, and we’re happy to help you find one that’s right for you. With that said, I’d like to briefly discuss one of my favorite formulas for increasing metabolism, burning fat, and balancing blood sugar: BerberTrim from Source Naturals. At its core, BerberTrim is powered by berberine, a compound found in plants like barberry. Research shows that berberine regulates blood sugar and insulin levels effectively. In addition, berberine activates AMPK, often called the body’s “metabolic master switch.” AMPK promotes fat breakdown while also inhibiting fat storage. To further support healthy blood sugar levels, BerberTrim includes chromium, cinnamon, and alpha-lipoic acid. To enhance fat burning and metabolism, the formula contains green tea and cayenne. Green tea promotes weight loss through caffeine, which boosts energy and metabolism, and EGCG, a compound that enhances fat burning and thermogenesis—the process by which the body generates heat by burning calories. Like EGCG, cayenne has also been shown to increase thermogenesis. To learn more or to discuss other options to support your weight loss goals, I invite you to stop in today. Mike Ventresca is the owner of Vital Choice Health Store located at 9243 Sprague Road in North Royalton’s Timber Ridge Plaza. The phone number is 440-885-9505 . This information is not intended to diagnose, treat, cure or prevent any disease.
By Michael Ventresca August 15, 2024
Non-alcoholic fatty liver disease (NAFLD) is a condition that currently affects nearly 25% of Americans and it’s on the rise. NAFLD is characterized by the buildup of fatty deposits in the liver in people with little or no alcohol intake and is the most common form of chronic liver disease. In some cases it can lead to liver damage similar to that of heavy alcohol use. NAFLD is said to effect approximately one out of every three women, and two out of every five men, aged 50 and older. One major problem is it doesn’t present obvious symptoms. While risk factors include high cholesterol, metabolic syndrome, obesity, sleep apnea and type 2 diabetes, most people have little or no symptoms. In fact, most people don’t know they have NAFLD until a blood test shows abnormal liver enzymes and damage may already be underway. While natural options like milk thistle and NAC are often thought of when discussing liver health, emerging research is pointing to none other than probiotics. Studies shows a healthy microbiome, fueled by a combination of probiotics combined with a prebiotic food source, creates a physical barrier keeping unwanted compounds and toxins in the gut where they belong instead of passing through the portal vein directly into the liver. FLORASSIST Liver Restore by Life Extension is a clinically studied daily formula that helps encourage a healthy ratio of liver-friendly gut bacteria. In clinical studies of both heavy and average weight subjects, the ingredients in Liver Restore encouraged healthy levels of liver enzymes used to measure liver health. It also helped improve measurements of C-reactive protein, a common health biomarker that is produced inside the liver. While full results were seen after 28 weeks, elevated liver enzymes were found to be back within the normal range after only seven weeks of use. Mike Ventresca is the owner of Vital Choice Health Store located at 9243 Sprague Road in North Royalton’s Timber Ridge Plaza. The phone number is 440-885-9505 . This information is not intended to diagnose, treat, cure or prevent any disease.
By Michael Ventresca June 12, 2024
A recent study published in the British Medical Journal Medicine (BMJ) reported a confusing outcome. The authors found regular use of fish oil supplements by healthy individuals could increase the risk of developing atrial fibrillation, an irregular heart rhythm. However, for those who already have the condition, taking fish oil supplements decreased the risk of further development and improved their health.  It’s important to note, this study was designed to report correlation, not causation. Additionally, the study had significant limitations, as it did not control for the amount, quality, or purity of the fish oil taken. Certainly, more research is needed. However, this topic highlights a key issue: the difference between the foundational and therapeutic use of supplements. Numerous studies have shown that fish oil supplements can provide therapeutic benefits. For example, taking a high dose of isolated omega-3s from fish oil can lower triglycerides, which I call therapeutic use—using a supplement as a natural medicine. On the other hand, there is a separate body of research that discusses the general health benefits of eating wild-caught fatty fish, like wild Alaskan salmon, three or more times per week. This is good foundational nutrition. The important question is: which do you need? For many, the answer is foundational. In that case, my favorite product is Wholemega by New Chapter . Wholemega is different from most fish oil supplements because it is not purified or isolated. Wholemega is cold-pressed, and just like a piece of wild salmon, naturally contains 16 different essential fatty acids, vitamin D, and even astaxanthin, the powerful antioxidant that gives salmon its color. Simply put, it is the closest thing to eating wild Alaskan salmon, something I think all health experts can agree on. This information is not intended to diagnose, treat, cure, or prevent any disease.
By Michael Ventresca March 19, 2024
In 1980, Dr. Hiroyuki Sumi, MD, a researcher for the Japan Ministry of Education discovered a special enzyme found in the fermented food natto had tremendous potential to improve cardiovascular health by preventing excessive clotting and promoting smoother blood flow. He called this enzyme nattokinase. Nattokinase works by regulating fibrin, a protein involved in blood clot formation. Think of fibrin as a mesh used by the body to slow down blood and help a clot to form when you cut your finger. When this system works properly, the fibrin does its job, but then is dissolved by another substance called plasmin.  When we’re young, we tend to have plenty of plasmin to dissolve the fibrin properly. However, due to normal aging as well as chronic inflammation and other conditions like hypertension and diabetes , plasmin levels decrease. The result is too much fibrin, leading to excessive clotting and slow-moving blood, increasing the risk of heart disease, thrombosis, and stroke. What makes nattokinase so special is its ability to break down fibrin by increasing plasmin production. In a sense, turning back the hands of time, it resets the proper fibrin response, and promotes smoother blood flow through the arteries. This in turn reduces the risk of blockages that can lead to heart attacks or strokes. In addition, nattokinase may also be able to lower blood pressure, improve cholesterol scores (by lowering LDL and raising HDL) and reduce inflammation. One of the best products nattokinase products available is Natto-K from Enzymedica. Natto-K uses a patented form of nattokinase proven to increase plasmin levels. For even greater support, Arthur Andrew’s Neprinol AFD offers unparalleled “anti-fibrin”, or fibrinolytic activity. It combines a high dose of nattokinase with serrapeptase, an enzyme used to treat inflammation. To be effective all nattokinase products must be taken on an empty stomach one hour before or two hours after a meal. Please note, if you are currently taking a prescription blood thinning medication do not take nattokinase without first talking to your doctor.
February 11, 2024
Watch Co-founder Michael Ventresca's recent discussion on WKYC's Good Company, shedding light on Vital Choice Health Store's crucial role as a community resource alongside hosts Joe and Terry.
By Michael Ventresca January 16, 2024
For years, we were told the key to strong bones was taking 1,000 milligrams of calcium daily. When studies showed that didn’t improve bone health, the updated advice was to take more. Unfortunately, studies now show that not only does taking 1,500 milligrams of calcium each day still not ensure strong bones, but it could also lead to an increased risk of heart attack or kidney stones as the additional calcium settles in places outside bone. Today, I’d like to share what I believe is a better option for bone health—one that many of our customers report has improved their bone density. First, to build strong bones, the body needs an absorbable form of calcium. Unfortunately, the most common forms simply aren’t very bioavailable. For example, the most common, calcium carbonate, is derived from limestone. When you take it, you are essentially eating chalk. Unlike plants, we are not built to get nutrition from rocks. Our bodies are designed to get nutrients from foods that naturally contain calcium, like green leafy vegetables. That’s where algae-based calcium comes in. Supplements made from algae-based calcium offer significant improvement in absorption and provide a host of other naturally occurring minerals, including boron, strontium, and silica that aid in uptake and, more important, the building of healthy, stronger bones. My favorite bone formula is Algae-Based Calcium from Vital Choice. In addition to providing algae calcium with additional minerals, it includes vitamins D3 and K2, both of which are critical to proper bone mineralization.  Mike Ventresca is the owner of Vital Choice Health Store, 9243 W. Sprague Road in North Royalton’s Timber Ridge Plaza. Call 440-885-9505 or visit VChoice.com . This information is not intended to diagnose, treat, cure, or prevent any disease.
By Michael Ventresca August 9, 2023
Over the past few months, berberine has exploded across social media as the next weight loss miracle pill with some calling it ‘nature’s Ozempic’. While I think these weight loss claims are exaggerated, it is true that berberine has been shown to provide support for a variety of conditions including irritable bowel syndrome, polycystic ovary syndrome, high cholesterol, heart disease, type 2 diabetes and yes, weight management. Today, let’s look at three of these, blood sugar, cholesterol and weight loss. Berberine has been extensively studied for its ability to lower blood sugar in clinical trials. It appears to work in several different ways including decreasing insulin resistance (effectively making the body’s insulin more effective) and increasing glycolysis, the process of breaking down sugar in cells. According to research, when compared to common medications like metformin, berberine was as effective as drugs, but with no significant side effects. Berberine has also been shown to help reduce blood lipids (cholesterol and triglycerides). Compared to statins, a class of drugs commonly prescribed for high cholesterol, berberine was found to lower total and LDL cholesterol but unlike the medications, additionally reduced triglycerides while increasing HDL. When looking at weight loss, the benefit appears to be from activating an enzyme inside cells called AMP-activated protein kinase (AMPK). AMPK plays a key role in regulating metabolism and energy levels and is found in cells throughout the body. While more studies are needed, preliminary studies show promise. One study from 2012 found that after taking berberine for 12-weeks participants lost an average of five pounds, while other studies found reductions in body weight, body mass index, and belly fat. While I always urge caution when social media claims sound too good to be true, berberine has been shown to provide a wide variety of health benefits without major side effects and therefore, may be worth a try. One note - berberine may interfere with the absorption of some antibiotics. Also, because of its ability to lower blood glucose, it is recommended to closely monitor your blood sugar levels if you are already taking oral hypoglycemic drugs. If you’re interested in trying berberine, one excellent option is Vital Choice’s Berberine . It provides the studied amount of 500mg of berberine HCl per capsule from sustainably grown barberry. Another great option is Enzymedica’s new Berberine Phytosome offering 9.6-times better bioavailability and Natural Factor's Berberine . Mike Ventresca is owner of Vital Choice Health Store located at 9243 Sprague Road in North Royalton. The phone number is 440-885-9505. This information is not intended to diagnose, treat, cure or prevent any disease.
By Michael Ventresca June 13, 2023
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